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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAR2A
All Species:
26.36
Human Site:
Y299
Identified Species:
38.67
UniProt:
P13861
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13861
NP_004148.1
404
45518
Y299
G
E
K
A
D
S
F
Y
I
I
E
S
G
E
V
Chimpanzee
Pan troglodytes
XP_001148361
477
52826
F373
G
D
S
A
D
S
F
F
I
V
E
S
G
E
V
Rhesus Macaque
Macaca mulatta
XP_001089109
461
51060
F357
G
D
S
A
D
S
F
F
I
V
E
S
G
E
V
Dog
Lupus familis
XP_541890
401
45078
Y296
G
E
K
A
D
S
F
Y
I
I
E
S
G
E
V
Cat
Felis silvestris
Mouse
Mus musculus
P12367
401
45371
Y296
G
E
K
A
D
S
F
Y
I
I
E
S
G
E
V
Rat
Rattus norvegicus
P12368
401
45522
Y296
G
E
K
A
D
S
F
Y
I
I
E
S
G
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509189
323
36258
E239
R
K
N
K
Q
E
V
E
E
N
D
S
V
E
I
Chicken
Gallus gallus
Q5ZM91
382
43332
F294
G
E
P
G
D
E
F
F
I
I
L
E
G
T
A
Frog
Xenopus laevis
NP_001084637
402
45172
F298
G
D
G
A
D
S
F
F
I
V
E
S
G
E
V
Zebra Danio
Brachydanio rerio
NP_001070838
397
44672
Y296
G
D
K
A
D
C
F
Y
I
V
E
S
G
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P81900
377
42730
Y280
G
D
A
A
D
G
M
Y
F
I
E
E
G
T
V
Honey Bee
Apis mellifera
XP_392905
383
43849
Y286
G
D
S
A
D
G
M
Y
F
V
E
D
G
I
V
Nematode Worm
Caenorhab. elegans
P30625
366
41449
F278
G
Q
P
G
D
E
F
F
I
I
L
E
G
E
A
Sea Urchin
Strong. purpuratus
Q26619
369
41770
Y277
G
D
G
A
D
G
C
Y
F
I
E
A
G
Q
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07278
416
47201
D316
Y
D
R
A
K
L
A
D
A
L
D
T
K
I
Y
Red Bread Mold
Neurospora crassa
Q01386
385
42138
F299
G
D
P
G
H
S
F
F
L
L
E
A
G
E
A
Conservation
Percent
Protein Identity:
100
58.4
61.1
91
N.A.
86.8
86.8
N.A.
58.6
35.1
64.8
71.2
N.A.
48.7
49.7
32.9
52.2
Protein Similarity:
100
68.3
70.7
94.5
N.A.
91.3
92
N.A.
69
52.7
80.6
83.6
N.A.
67.8
69
54.9
69
P-Site Identity:
100
73.3
73.3
100
N.A.
100
100
N.A.
13.3
46.6
73.3
80
N.A.
53.3
46.6
46.6
46.6
P-Site Similarity:
100
93.3
93.3
100
N.A.
100
100
N.A.
33.3
53.3
93.3
93.3
N.A.
60
60
60
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37.2
35.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.2
51.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
40
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
75
0
0
7
0
7
0
0
13
0
0
19
% A
% Cys:
0
0
0
0
0
7
7
0
0
0
0
0
0
0
7
% C
% Asp:
0
57
0
0
82
0
0
7
0
0
13
7
0
0
0
% D
% Glu:
0
32
0
0
0
19
0
7
7
0
75
19
0
69
0
% E
% Phe:
0
0
0
0
0
0
69
38
19
0
0
0
0
0
0
% F
% Gly:
88
0
13
19
0
19
0
0
0
0
0
0
88
0
0
% G
% His:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
63
50
0
0
0
13
7
% I
% Lys:
0
7
32
7
7
0
0
0
0
0
0
0
7
0
0
% K
% Leu:
0
0
0
0
0
7
0
0
7
13
13
0
0
0
0
% L
% Met:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
0
0
0
0
7
0
0
0
0
0
% N
% Pro:
0
0
19
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
7
0
0
7
0
0
0
0
0
0
0
0
7
0
% Q
% Arg:
7
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
19
0
0
50
0
0
0
0
0
57
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
7
0
13
0
% T
% Val:
0
0
0
0
0
0
7
0
0
32
0
0
7
0
63
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
50
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _